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Athletic pseudonephritis is typically caused by the excessive release of myoglobin into the bloodstream due to muscle injury or intense physical exertion, such as in endurance sports. This myoglobin can then be filtered by the kidneys, leading to symptoms that mimic those of true nephritis, such as hematuria and proteinuria, without actual kidney inflammation. It often occurs in athletes who experience muscle strain or rhabdomyolysis. Proper hydration and monitoring of kidney function are essential to manage this condition.

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