50 - 23 were caught by Randy Moss.
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It is 50 by Tom Brady of the New England Patriots in the 2007 season. Manning is second and Marino 3rd.
As of the 2008 season, that is Tom Brady of the New England Patriots with 50 TD passes in 2007.
Peyton Manning's 49 TD passes in 2004 broke the record set by Dan Marino of the Miami Dolphins who threw 48 TD passes in 1984. Manning's record was eclipsed by Tom Brady of the Patriots who threw 50 TD passes in 2007.
In 2007 the Patriots Quarterback Tom Brady broke the record for most TD passes in a season with 50. The previous record was broken in 2004 by Peyton Manning. Tom Brady threw 23 TD passes to Randy Moss, which is also a record. The Patriots broke the record for most points per game and they broke the TD record too. Wes Welker had 112 catches and their kicker made all of the PAT. They were not last in running the ball either and they were like 28th but, that is pretty good when your quarterback is throwing 325ypg ( 4,800 altogether).
Tom Brady in 2007 (50 TD's) Peyton Mannin in 2004 (49 TD's) Dan Marino in 1984 (48 TD's) and 86' (44 TD's) Kurt Warner in 1999 (41 TD's)