They have never made an appearance in the Final 4.
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Thorugh March Madness 2008, the University of Missouri has never been to a men's final four.
Eleven times.
never - elite eight two times
Including the 2012 NCAA Tournament: Brigham Young University has made the Tournament 28 times and has never made it to the Final Four. Missouri is second, with 26 appearances without ever making the Final Four. Xavier, which so far has won in the 2012 tournament as this is being written, is third with 22 years without an appearance.
twice