Not in the 2008 season. Interleague games for the Yankees are 6 with the Mets and 3 each with the Astros, Padres, Reds, and Pirates.
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In 2010, the Yankees played the Diamondbacks from June 21-23 in Arizona, as part of their interleague schedule.
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In 2013, the two teams played their interleague series in New York (April 16-18).
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The Arizona Diamondbacks defeated the Yankees in the 2001 World Series.
The Diamondbacks have played in and won one World Series. In 2001, they defeated the New York Yankees 4 games to 3.
The Arizona Diamondbacks beat the New York Yankees in a seven-game series.
7-12 In 2010 the Diamondbacks went 1-2 against the Yankees In 2007 the Diamondbacks went 0-3 against the Yankees In 2004 the Diamondbacks went 1-2 against the Yankees In 2002 the Diamondbacks went 1-2 against the Yankees In 2001 the Diamondbacks went 4-3 against the Yankees The Diamondbacks didn't play the Yankees in 1998-00, 03, 05-06, 08-09, 11
In 2010, the Yankees played a three game interleague series in Arizona from June 21-23.