yes he did around 1934
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Lou Gehrig's Major League debut was on June 15, 1923 as a pinch hitter.
On May 2, 1939, the day when Lou Gehrig's consecutive game streak ended, he was replaced by Ellsworth "Babe" Dahlgren.
Gehrig's nickname was "The Iron Horse", because of his consectutive game record. He never let anything keep him from playing. X-rays of his hands after he died showed that he had broken every one of his fingers at least twice - no one knew he had ever broken them at all.
Lou Gehrig's diagnosis was confirmed on June 19, 1939. His last game was on April 30, 1939.
Lou Gehrig took himself out of the lineup before the game played on May 2, 1939, ending his consecutive streak at 2,130 games.