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The increase in estrogen when going from Alesse to Ortho Tricyclen could cause breast tenderness, which should disappear within the first three cycles. If it lasts longer than that, is accompanied by other symptoms, or if it's driving you nuts, contact your health care provider for advice anda possible change in pills.

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Q: Are sore nipples a normal side effect if you have been on Alesse for three years and have recently switched to Tricylcen?
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