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It means that the horse is racing on the medication Lasix for the first time. Lasix is the trade name for furosemide and is a diuretic used to prevent pulmonary bleeding in race horses. Approx. 80% of U.S. race horses run usuing Lasix.

Subsequent uses of lasix will still be noted in the race program, sans "1."

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Q: What does L1 mean in horse race under Med heading?
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