The top selling Baseball card would be a card that is popular, and in high demand, plenty on the market, and would most likely have a relatively low value. You would need to go on eBay to find out this information. This would be the card that is listed, and sold the most. If you mean "what is the most expensive baseball card?" see Related Questions below for the answer.
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The T206 Honus Wagner is generally considered to be the most expensive baseball card in the world. Less than 100 are believed to exist.