Not only in youth Baseball but in all levels of baseball, a closed base means that the next base that a base runner needs to get to has a runner already on the bag.
E.G.: There's a runner on first and second, so a ground ball will force a throw from second base to first base considering that those bases are "closed" with base runners.
In a bases loaded situation, all bases are "closed" because all bases have a base runner and the batter is considered on home plate.
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