Payton Manning with 4,135 passing yards and 26 passing touchdowns
As of the 2008 season, Brett Favre with 442.
The record for the most passing yards by a college quarterback in his career is held by Timmy Chang. Chang played for University of Hawaii from 2000-2004 and managed to throw for an astonishing 17,072 yards.
David Klingler with 716 yards
Boston College quarterback Doug Flutie completed 16 of 37 passes for 287
1,261.6 It is achieved by passing for 99-yard touchdowns on each attempt.The lowest is -731.6, which is achieved by passing for a 99-yard loss on each attempt.
Steve young had 340 yards in a playoff game which is the most passing yards a quarterback has thrown in a NFL game.