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For a career, that would be Mark McGwire who hit a home run every 10.6 at bats. Second all time is Babe Ruth with a home run every 11.8 at bats.

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Q: Who in MLB has the most home runs per at bat?
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Related questions

Did the MLB player Miguel Cabrera hit a Home Run in his first MLB at bat?

No, he hit a walk off home run in his first major league game but it was not his first at-bat.


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