Brett Favre, with 169 wins as a starter.
Brett favre
Tom brady
Steve Davis
darrell bevel
Brett Farve
Troy Aikmen
terry bradshaw for the steelers
Tom Brady
John Elway
Colt McCoy holds the record for now. Kellen Moore will pass Colt's record to set the bar even higher. Kellen also will set a record for the most Touchdowns for an FBS Quarterback by the end of this years season. 2011-12
Colt McCoy with 44 wins. He is 44-7 in 51 starts with Texas. David Greene is second with 42 wins for Georgia from 2001-2004. His record was 42-10 as a starter.
Joe Montana