Ernie Banks hit the most home runs at Wrigley Field with 290. Coming in second is Billy Williams with 241. The first home run at Wrigley Field was by Art Wilson of the Chicago Whales in a Federal League game on April 23, 1914.
In the 8th inning of Ken Burn's "Baseball" the film sequence implies Mantle hit a home run at Wrigley! I suspect he never played an official game at Wrigley Field!!
Wrigley Field in Chicago in 1932.
Richie Sexson hit a 503 foot home run to center field in 2004
May 12, 1970 at Chicago's Wrigley Field, Banks hit his 500th home run.
248 a major league record
Sammy Sosa with 293 followed by Ernie Banks with 290.
I don't believe the left field stands in Wrigley Field has a roof, so probably not.
Bj upton 757