Jose Molina
The last time the Chicago Cubs played at Yankee Stadium was on June 30, 2019, during a regular season interleague matchup. This game was held at the new Yankee Stadium, which opened in 2009, replacing the original Yankee Stadium. The Cubs and Yankees have a storied history, but this was their most recent encounter at the Yankees' home field.
Baltimore Orioles pitcher Chris Waters gave up the last home run at Yankee Stadium. It was given up to Jose Molina.
REGGIE JACKSON
Yankee Stadium
Jose Molina hit the last home run at the old Yankee Stadium in the 4th inning. Johnny Damon hit the second to last home run in the third inning.
Jose Molina hit the last home run in the old Yankee Stadium off of Baltimore Orioles pitcher Chris Waters. It was in the bottom of the fourth inning.
derek jeter
The last of Harmon's 22 career home runs at Yankee Stadium came on June 5, 1968 off of Mel Stottlemyre in the 5th inning of a Twins 7-2 loss.
Daffy Duck
On September 21, 2008, catcher José Molina hit the last home run at the old Yankee Stadium. He hit it in the 4th inning against Baltimore Orioles pitcher Chris Waters.This is accurate for the time period involved. As there have been 3 stadiums, a date is required. As example, the last home run in the original 1923 stadium, which is one of the "old" Yankee Stadiums, needs clarification.
Dustin Pedroia
The last game played at Yankee Stadium was on September 21, 2008 against the Baltimore Orioles.