The pitcher that struck out the most batters in history is Nolan Ryan. He has struck out 5,714 batters during his career from September 11, 1966 until September 22, 1993.
Roger Clemens with 20 struck out batters! XD
Nolan Ryan had 5,714 career strikeouts.
Nolan Ryan struck out the most batters, but Reggie Jackson struck out the most at the plate.
Nolan Ryan holds 5,714 strikeouts for his career and to this point no one else in the majors have struck out more than 5000 batters.
I believe you mean How many people did Nolan Ryan "strike out". And he "struck out" 5,714 people.
In the 2011 season, he has 147 strikeouts. In his career, he has struck out 1,861 batters