It depends on which game you mean and in which league.
Steelers
The Tennessee Lady Volunteers have the most wins.
San Francisco Giants with 10,184 wins
Detroit
The current UConn womens team.
As of the start of the 2007 season, the Division 1-AA team with the most all time wins was Yale with 839.
North Carolina Tarheels when you filter in all NCAA sports
All-Time College Basketball Team With Most Wins up til 08-09 season* University of Kentucky with a record of 1988 wins and 635 lossesAll-Time College Football Team With Most Wins 1869-2008* Michigan with a record of 872-295-36
The Chicago Bears are first in all time wins.
Detroit Red Wings
lsu Mississippi State has the most wins with 2280. LSU is 7th on the list with 2106.
The Chicago Bears