Rafael Novoa debuted on July 31, 1990, playing for the San Francisco Giants at Candlestick Park; he played his final game on October 3, 1993, playing for the Milwaukee Brewers at County Stadium.
Roberto Novoa debuted on July 29, 2004, playing for the Detroit Tigers at Comerica Park; he played his final game on September 30, 2006, playing for the Chicago Cubs at Wrigley Field.
Rafael Almeida debuted on July 4, 1911 and played his final game on July 18, 1913.
Rafael Batista debuted on June 17, 1973 and played his final game on April 27, 1975.
Rafael Belliard debuted on September 6, 1982 and played his final game on April 9, 1998.
Rafael Betancourt debuted on July 13, 2003 and played his final game on August 22, 2013.
Rafael Bournigal debuted on September 1, 1992 and played his final game on October 3, 1999.
Rafael Carmona debuted on May 18, 1995 and played his final game on June 12, 1999.
Rafael Dolis debuted on September 26, 2011 and played his final game on May 26, 2013.
Rafael Santo Domingo debuted on September 7, 1979, playing for the at ; he played his final game on September 30, 1979, playing for the at .
NFL player Rafael Bush played for South Carolina State.
Rafael Batista debuted on June 17, 1973, playing for the Houston Astros at Astrodome; he played his final game on April 27, 1975, playing for the at .
Rafael Medina debuted on April 2, 1998, playing for the Florida Marlins at Joe Robbie Stadium; he played his final game on September 26, 1999, playing for the Florida Marlins at Pro Player Stadium.