Luke French debuted on May 15, 2009, playing for the Detroit Tigers at Comerica Park; he played his final game on October 1, 2010, playing for the Seattle Mariners at Safeco Field.
Luke Allen debuted on September 10, 2002 and played his final game on July 17, 2003.
Luke Appling debuted on September 10, 1930 and played his final game on October 1, 1950.
Luke Boone debuted on September 9, 1913 and played his final game on September 2, 1918.
Luke Carlin debuted on May 10, 2008 and played his final game on May 30, 2012.
Luke Easter debuted on August 11, 1949 and played his final game on May 4, 1954.
NBA player Luke Babbitt played for Nevada.
NBA player Luke Ridnour played for Oregon.
NFL player Luke Bowanko played for Virginia.
NFL player Luke Willson played for Rice.
NFL player Luke Stocker played for Tennessee.
NFL player Luke Kuechly played for Boston College.
NFL player Luke Joeckel played for Texas A&M.