Hector Villanueva debuted on June 1, 1990, playing for the Chicago Cubs at Wrigley Field; he played his final game on June 13, 1993, playing for the St. Louis Cardinals at Busch Stadium II.
NBA player Charlie Villanueva played for Connecticut.
NFL player Alejandro Villanueva played for Army.
Hector Almonte debuted on July 26, 1999 and played his final game on September 28, 2003.
Hector Ambriz debuted on April 30, 2010 and played his final game on July 26, 2013.
Hector Cruz debuted on August 11, 1973 and played his final game on July 15, 1982.
Hector Fajardo debuted on August 10, 1991 and played his final game on June 18, 1995.
Carlos Villanueva debuted on May 23, 2006, playing for the Milwaukee Brewers at Miller Park; he played his final game on September 28, 2013, playing for the Chicago White Sox at U.S. Cellular Field.
Elih Villanueva debuted on June 15, 2011, playing for the Florida Marlins at Sun Life Stadium; he played his final game on June 15, 2011, playing for the Florida Marlins at Sun Life Stadium.
Hector Gimenez debuted on September 25, 2006, playing for the at ; he played his final game on June 29, 2013, playing for the Chicago Cubs at Wrigley Field.
Hector Martinez debuted on September 30, 1962, playing for the at ; he played his final game on June 4, 1963, playing for the Kansas City Athletics at Municipal Stadium I.
Hector Villanueva played in 28 games at catcher for the Chicago Cubs in 1992, starting in 26 of them. He played for a total of 666 outs, equivalent to 24.67 9-inning games. He made 155 putouts, had 20 assists, and committed 4 errors, equivalent to .162 errors per 9-inning game. He had one double play. He had 3 passed balls, 12 wild pitches, 21 opponent stolen bases, and 11 opponent caught stealings. His zone rating was 1.
Charlie Villanueva plays for the Detroit Pistons.