Francisco Rosario debuted on May 6, 2006, playing for the Toronto Blue Jays at Rogers Centre; he played his final game on September 17, 2007, playing for the Philadelphia Phillies at Citizens Bank Park.
Jimmy Rosario debuted on April 8, 1971, playing for the San Francisco Giants at Candlestick Park; he played his final game on June 21, 1976, playing for the Milwaukee Brewers at County Stadium.
Sandy Rosario debuted on September 23, 2010, playing for the Florida Marlins at Dolphin Stadium; he played his final game on September 17, 2013, playing for the San Francisco Giants at AT&T Park.
Enerio Del Rosario debuted on May 24, 2010 and played his final game on September 29, 2012.
NFL player Dante Rosario played for Oregon.
Francisco Rosario played in 23 games at pitcher for the Philadelphia Phillies in 2007, starting in none of them. He played for a total of 79 outs, equivalent to 2.93 9-inning games. He made one putout, had 4 assists, and committed no errors, equivalent to 0 errors per 9-inning game. He had one double play.
Francisco Barrios debuted on August 18, 1974 and played his final game on June 3, 1981.
Francisco Cabrera debuted on July 24, 1989 and played his final game on September 24, 1993.
Francisco Cervelli debuted on September 18, 2008 and played his final game on April 26, 2013.
Francisco Cordero debuted on August 2, 1999 and played his final game on August 1, 2012.
Francisco Cordova debuted on April 2, 1996 and played his final game on August 8, 2000.
Francisco Cruceta debuted on September 21, 2004 and played his final game on June 2, 2008.
Wilin Rosario debuted on September 6, 2011, playing for the Colorado Rockies at Coors Field; he played his final game on September 17, 2013, playing for the Colorado Rockies at Coors Field.