As of the 2007 season: In the NFL, the record for career rushing yards is held by Emmitt Smith with 18,355. In college football, the Division 1-A record for career rushing yards is held by Ron Dayne with 6,397.
Rushing is when they run the football and the gain yards.
Marshall Faulk Reggie Bush - 8.7 YPC (2005) 200 carries for 1740 yards
Denard Robinson from the University of Michigan holds the record for most rushing yards by a quarterback in a season with 1,538 yards. Robinson also holds the record for most career rushing yards by a QB in NCAA history with 4,495 yards.
1971 Oklahoma Sooners
Rushing yards are yards gained by running the ball instead of passing.