In 2000, Keith Osik played in 46 games, all for the Pittsburgh Pirates, and batting in all of them. He had 123 at bats, getting 36 hits, for a .293 batting average, with 1 sacrifice hit, 0 sacrifice flies, and 22 runs batted in. He was walked 14 times, and was hit by the pitch 5 times. He struck out 11 times. He hit 6 doubles, 1 triple, and 4 home runs.