99-63.
The team with the best regular season record to lose was the 1906 Chicago Cubs who went 116-36 and lost the World Series to the Chicago White Sox.
The Chicago White Sox beat the Chicago Cubs in the 1906 World Series.
In the 2005 World Series, the Chicago White Sox swept the Houston Astros in four games.
The Chicago White Sox defeated the Chicago Cubs 4 games to 2 in the 1906 World Series, the third World Series to be played.
Answer The 1906 Chicago Cubs had a record of 116-36 for a winning percentage of .763. However, they went on to lose the World Series 4 games to 2 against their rivals from the South Side of town, the Chicago White Sox. The Chicago White Sox won Chicago's very first World Series Title and as it stands they've also won the city's most recent one as well. (2005)
The Chicago White Sox have won the World Series in 1906, 1917, and 2005.
Short Answer: White SoxThe Chicago White Sox won three world series ... 1906, 1917, and 2005, while the Chicago Cubs have only won two ... 1907 and 1908.
As of 2009 the Chicago White Sox last won the World Series in 2005.
The Chicago White Sox played the Houston Astros in the 2005 World Series. The White Sox swept the Astros in 4 games giving Chicago it's first Championship in 88 years!
103 years of not winning a world series is an all time record.
The Chicago White Sox won 99 regular season games and 11 games in the post season.
The Chicago White Sox last won the World Series in 2005.