tom brady
Tom Brady holds the record with 50 touchdown passes
Jerry Rice currently holds the single season record with 22 touchdowns in the 1987 season with the San Francisco 49ers
Barry Sanders with 39.
Reggie bush
Jerry Rice
gale sayers
Ed Smith
Mesghina 107 touchdowns in 1999.
Randy Moss(New England Patriots) with 24 touchdowns
Barry Sanders had 39 TD's in his 1988 season.
joe dimmagio