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The MLB record for home runs in a game is 4 and is shared by 15 players. 12 players hit their four home runs in a nine inning game and 3 others did it in an extra innings game. More information about home run records can be found at the link below: http://www.baseball-almanac.com/recbooks/rb_hr4.shtml The most home runs by one team in one game is 10 set by the Toronto Blue Jays against the Baltimore Orioles on Sept. 14, 1987. The National League record is 9 set by the Cincinnati Reds against the Philadelphia Phillies on Sept. 4, 1999.

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Q: What is the record for most home runs in a major league game?
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