They scored 8 in the 2nd inning of some game. My source doesn't give the date, but that is the most they've scored in an inning this year.
Dave Collins. Collins scored in the 4th inning of the Mariners game against the Angels on April 8, 1977.
Usually it's the ninth inning because that's when teams rally from behind.
Albie Pearson. Pearson scored on a Ted Kluszewski home run in the first inning of the first ever Angels regular season game on April 11, 1961 against the Baltimore Orioles.
The highest number of runs scored in one inning was by the Kansas City Royals in 1979. In the fourth inning on June 14, 1979 the Royals scored 4 off of a grand slam by George Brett.
The most runs scored by a single team in the first inning is 16 by the Boston Beaneaters against the Baltimore Orioles in 1894. The most runs scored by both teams in the first inning is 16 held by Boston and Baltimore as described above (Boston 16, Baltimore 0) and the Oakland Athletics and California Angels in a game in 1996 where Oakland scored 13 runs and California scored 3 runs.
The term 'unanswered run' means one team scored and the other team has not scored any runs afterwards. For example, let's say the home team scored one run in the second inning, two runs in the third inning, and one run in the fourth inning while the visiting team has been held scoreless after scoring one run in the first inning. You might hear an announcer say "The home team has scored four unanswered runs after the visiting team scored in the first inning'.
The Yankees scored 12 runs in the first inning against the Orioles.
Just recently the angels scord 10 runs in the 13th to beat the orioles and that was the largest margin of victory in extras since 1963
Bert Campaneris of the Kansas City Athletics on September 8, 1965. Campaneris' positions by inning: 1st inning: shortstop 2nd inning: second base 3rd inning: third base 4th inning: left field 5th inning: center field 6th inning: right field 7th inning: first base 8th inning: pitcher 9th inning: catcher The game, played against the California Angels in Kansas City, went 13 innings before the Angels won 5-3. In Campaneris' one inning of pitching, he gave up 1 run on 1 hit and 2 walks. He also struck out a batter (Bobby Knoop). He made an error in right field and the Angels one run scored in the 6th inning was unearned. He was replaced in the 10th inning by catcher Rene Lachemann.