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Per the Yankee's web site, the most runs scored by an opponent at home was 22 in 2004 by the Cleveland Indians. On the road it was 24 back in 1928 again by Cleveland. They are currently have 20 scored against them as of 6:20pm on Saturday, April 18, 2009

Right now the Indians are ahead 20-2 against the Bronx Bombers.... Right now the Indians are ahead 20-2 against the Bronx Bombers....

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Q: What is the most runs scored against the Yankees in one game?
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