Dorsette 280 yds
Cam Newton
November 4, 2007, 1:00 pm. He played against the Chargers and broke the record of the most rushing yards in a single game, he rushed for 296 yards. This was also in his rookie season!
Flipper Anderson holds the Rams team record and the NFL record for receiving yards in a single game with 336 yards in a game against the Saints in 1989.
Hall of Fame quarterback Troy Aikman holds the record for the most passing yards in a Thanksgiving day game. He threw for 455 yards versus the Minnesota Vikings 11/26/1998.
Dave Wilson
In the NBA the best rookie has to go to Larry Bird's rookie season. the MLB the best rookie is probably Babe Ruth's home run rookie record. In the NFL the best rookie was most likely Jim Brown who not only gained over five hundred yards but was named MVP.
On December 20, 2009, against the Green Bay Packers, Ben Roethlisberger set the Steelers single game record for most passing yards. He completed 29 of 46 passes for 503 yards.
Troy Williamson
Marcus depree
Adrian Peterson holds the record for most rushing yards in a game, 296, while playing as a rookie for the Minnesota Vikings against the San Diego Chargers on November 4, 2007. Peterson scored 3 touchdowns. Even more amazing is that 253 of those yards were in just the second half of the game, which the Vikings won 35-17.
The Denver Bronco's quarterback who holds the record for the most passing yards in a game was Peyton Manning. He passed the record of Drew Brees
510 yrds