Three of the most prominant player to wear number 10 for the Giants include Fran Tarkenton, Brad Van Pelt, and Eli Manning.
Punter Jeff Feagles between 2006-2009 and backup quarterback Sage Rosenfels in 2010.
Rodney Hampton, and Steve Thurlow are former starting running backs who wore number 27 for the Giants. Present starting running back (as of 2007) Brandon Jacobs now wears this number for the Giants.
For the Houston Astros, 35 different players have worn the number 22 from 1962 to 2013. The Yankees have had 58 players wear number 22 from 1929 to 2013.
Graig Nettles from 1973 to 1983
The only two distinguished players who have worn number 43 for the New York Giants were Pro Bowl defensive back Carl "Spider" Lockhart (1965-75) and Pro Bowl safety Terry Kinard (1983-89). Defensive back Percy Ellsworth (1996-99) is the only other player to have worn number 43 for more than one season (since 1950).
There have only been two players (Herb Karpel and Gus Niarhos) and two managers (Casey Stengel and Bucky Harris) who have worn #37 for the Yankees. Casey Stengel was the only Yankee to wear #37, who has also played for the Giants organization. That was the New York Giants from 1921-1923.
It depends on which giants you are talking about: New York Giants (football) or San Francisco Giants (baseball). If you are talking about football, then number 62 is Conrad Goode. If you are talking about baseball, number 62 has been worn by Bob Howry, Wilson Delgado, and Jacob Cruz.