52
The largest margin of victory was 30 pts in a champtionship game. Not sure about just tournament games.
1965 regional - Princeton 110 - Providence 70
45
In 1963, Loyola set the NCAA tournament record for largest margin of victory (69 points) with a 111-42 victory over Tennessee Tech in the first round.
52-2
U Conn 105; Idaho 37 - 68 points - 3/23/2013
7
I'm pretty sure UNLV beat Duke by 30pts in the 1990 title game
Houston
The largest margin of victory recorded in a horse race was by Secretariat in the Belmont Stakes in 1973, where he won by 31 lengths.
Largest Margin of Victory: Sam Morgan vs Forrest Petz at Ultimate Fight Night 6: One judge scored the fight 30-23 2nd largest margin: Nate Quarry vs Kalib Starnes at UFC 83: One judge scored the fight 30-24
Through Super Bowl XLII, the average margin of victory is 15 points. Margin of victory 1-7 points: 13 games Margin of victory 8-14 points: 9 games Margin of victory 15-21 points: 10 games Margin of victory 22-28 points: 4 games Margin of victory over 28 points: 6 games Smallest margin of victory: 1 point in Super Bowl XXV - New York Giants 20, Buffalo Bills 19 Largest margin of victory - 45 points in Super Bowl XXIV - San Francisco 49ers 55, Denver Broncos 10