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There has been no universal mechanism found to explain skeletal muscle fatigue. With the onset of intense exercise, muscle force has been shown to fall, which is often illustrated as a sign of fatigue. As ATP supplies the immediate energy to the muscle cell, the relationship between ATP and fatigue has been a topic of interest among researchers. During muscle contraction the majority of ATP is used for cross bridge cycling, ion pumps and transporters, and chemical signalling cascades. A fall in [ATP] would result in the development of rigor and goes against the viability of the cell. It is proposed that whole muscle [ATP] does not fall with repeated contraction, though there may be differences in [ATP] between fiber types with fatigue. Rather, fatigue is a protective mechanism by the muscle to preserve [ATP] accomplished by down regulating cellular processes that use ATP for energy
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The force of a muscle contraction is not affected by?
the amount of ATP in the muscle cells
How do you explain fatigue in the muscular system?
Accumulation of lactic acid in the muscle from anaerobic ATP production.
Decreasing tension in a muscle due to lowering levels of ATP is called?
Disentration
How can a skeletal muscle produce additional ATP when there is not enough oxygen?
Anaerobic fermentation enables a cell to produce ATP in the absence of oxygen but the ATP yield is very limited and the process produces a toxic end product, lactic acid, which is a major factor in muscle fatigue.
Why would a defect in the mitochondria cause fatigue?
Because mitochondria synthesize, or produce ATP, which is a form of energy. If the mitochondria isn't working properly, then energy production will be affected, causing fatigue.
Does muscle relaxation does not require ATP?
Both muscle relaxation and muscle contraction require ATP.
When does muscle fatigue occur?
Muscle Fatique occurs when low o2 conditions deplete Atp and cp stores acaerobic respiration creates lactic acid. drops in ph and o2 debt lead to failure of the muscle to maintaain contractions
What type of muscle is rich in ATP?
Muscle fibers are rich in ATP. All muscle fiber types are rich in ATP (having many mitochondria).
What is phosphogen?
The Phosphogen SystemSkeletal muscle uses large amounts of ATP during active contraction. Skeletal muscle can produce limited amounts of ATP from the breakdown of stored phosphocreatine. As ATP is used and ATP levels decrease, phosphocreatine is used to make ATP from ADP. When the cell is resting and ATP levels increase due to aerobic glucose catabolism, phosphocreatine is produced from ATP and creatine. This mechanism can produce 1 ATP for every molecule of phosphocreatine present. Muscle cells normally have enough phosphocreatine to produce ATP for several minutes at rest but only 10-15 seconds during exercise.
What causes muscular fatigue after just a few minutes of intense exertion?
Reduction in the effectiveness of a muscle or muscle group reflected by a decline in peak tension. Local muscular fatigue may be due to one or more reasons, such as failure of a motor nerve to transmit nerve impulses to the muscle; fatigue at the neuromuscular junction through depletion of neurotransmitters; inability of the contractile mechanism (the actin and myosin myofilaments) to generate force; accumulation of protons from lactic acid in the muscle; depletion of ATP and phosphocreatine; or failure of the central nervous system to initiate and relay nerve impulses to the muscle. The most probable sites of local muscular fatigue are the neuromuscular junctions, the contractile mechanism of the muscle itself, and the central nervous system. Fatigue at the neuromuscular junction, which might be more common in fast twitch fibres, is probably due to depletion of http://www.answers.com/topic/acetylcholine. Fatigue within the contractile mechanism may be caused by accumulation of protons, depletion of ATP and phosphocreatine; depletion of muscle glycogen; dehydration; or lack of oxygen and inadequate blood flow.
Why is atp important in muscles?
ATP is important in muscle contraction. ATP is high energy bond which gives you energy required for muscle contraction.
Why di muscle cells have many mitochondria?
Muscle requires a lot of ATP , mitochondria produces ATP
