No. On April 15, 2012, the Minnesota Twins lost to the Texas Rangers, 4-3.
On August 27, 2012, the Seattle Mariners defeated the Minnesota Twins, 1-0.
The Twins first regular season game in the Metrodome was April 6, 1982 against the Seattle Mariners. The Twins lost that game 11-7.
On June 9, 2012, the Minnesota Twins will be playing the Chicago Cubs during the day.
Tyler Robertson debuted on June 26, 2012, playing for the Minnesota Twins at Target Field; he played his final game on April 5, 2013, playing for the Minnesota Twins at Target Field.
The Minnesota Twins played indoors until April 12th, 2010, when they played they're first regular season game at their new home, Target Field.
Fred Bruckbauer debuted on April 25, 1961, playing for the Minnesota Twins at Metropolitan Stadium; he played his final game on April 25, 1961, playing for the Minnesota Twins at Metropolitan Stadium.
Earl Battey started at catcher in the first ever Twins regular season game on April 11, 1961.
Friday, April 6th, 2012
Sean Burroughs debuted on April 2, 2002, playing for the San Diego Padres at Qualcomm Stadium; he played his final game on April 30, 2012, playing for the Minnesota Twins at Target Field.
Keith Garagozzo debuted on April 5, 1994, playing for the Minnesota Twins at Hubert H Humphrey Metrodome; he played his final game on April 28, 1994, playing for the Minnesota Twins at Hubert H Humphrey Metrodome.
Dave Gassner debuted on April 16, 2005, playing for the Minnesota Twins at Hubert H Humphrey Metrodome; he played his final game on April 21, 2005, playing for the Minnesota Twins at Hubert H Humphrey Metrodome.
Carlos Pulido debuted on April 9, 1994, playing for the Minnesota Twins at Hubert H Humphrey Metrodome; he played his final game on April 24, 2004, playing for the Minnesota Twins at Hubert H Humphrey Metrodome.