Yes.
John Roper debuted on May 16, 1993, playing for the Cincinnati Reds at Riverfront Stadium; he played his final game on September 11, 1995, playing for the San Francisco Giants at Candlestick Park.
John Reilly debuted on May 18, 1880, playing for the Cincinnati Reds at Bank Street Grounds; he played his final game on October 3, 1891, playing for the Cincinnati Reds at League Park I in Cincinnati.
John Courtright debuted on May 6, 1995, playing for the Cincinnati Reds at Riverfront Stadium; he played his final game on May 6, 1995, playing for the Cincinnati Reds at Riverfront Stadium.
John Gillespie debuted on April 12, 1922, playing for the Cincinnati Reds at Crosley Field; he played his final game on September 30, 1922, playing for the Cincinnati Reds at Crosley Field.
John Magner debuted on July 14, 1879, playing for the Cincinnati Reds at Avenue Grounds; he played his final game on July 14, 1879, playing for the Cincinnati Reds at Avenue Grounds.
1990
No
Cincinnati Reds swept the Okland Athletics 4-0.
John Noriega debuted on May 1, 1969, playing for the Cincinnati Reds at Crosley Field; he played his final game on August 9, 1970, playing for the Cincinnati Reds at Crosley Field/Riverfront Stadium.
NOpe
The current Cincinnati Reds franchise began play in the American Association in 1882 as the Cincinnati Red Stockings.
Devin Mesoraco plays for the Cincinnati Reds.