Most Interceptions ThrownGeorge Blanda (Houston Oilers '62) threw the most interceptions in one season.
The quarterback who has thrown the most interceptions is Brett Favre, who through the 2010 season has thrown 336 career interceptions. The record for most interceptions by a defensive player in a career is held by Paul Krause, who intercepted 81 career passes.
Check out the link attached about Jim Hardy he holds the nfl-record of 8 interceptions thrown in a single game. A long long time ago.
In a season for most thrown interceptions is George Blanda, Houston, 1962 with 42. In a season for most passes intercepted is Dick (Night Train) Lane, Los Angeles, 1952 with 14.
The career interception record is held by Paul Krause with 81 interceptions. The single-season record is held by Dick "Night Train" Lane with 14 interceptions. The most interceptions caught in a game is 4 by 20 players.
Through the 2010 season: 1) Brett Favre - 336 2) George Blanda - 277 3) John Hadl - 268
Rich Gannon of the Oakland Raiders threw 5 interceptions in Super Bowl XXXVII versus the Tamp Bay BUccaneers