The 49ers, like most NFL teams, have numbers on their helmets to identify the players on the field. Each player is assigned a specific number, which is displayed on their helmet and jersey. This helps coaches, officials, and fans distinguish between players and know who is on the field at any given time. The number on a player's helmet is also often used to identify them in statistics and game records.
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That is out of respect to Sean Taylor, the Redskins safety that was murdered earlier this week. All teams will be wearing a '21' on their helmets for their games.
the Green Bay Packers wear that number cause of the defenseive star reggie white
They don't. New England is the only team with 91 on their helmets, in honor of Marquise Hill a defensive end that died recently. The other teams have a 21 for Sean Taylor.