The NFL record for sacks in a game is 12 and has been done 5 times:
1) Dallas vs. Pittsburgh, Nov. 20, 1966
2) St. Louis vs. Baltimore, Oct. 26, 1980
3) Chicago vs. Detroit, Dec. 16, 1984
4) Dallas vs. Houston, Sept. 29, 1985
5) NY Giants vs. Philadelphia, Sept. 29, 2007
7 sacks by Derrick Thomas played on Kansas Cheifs
Derrick Thomas with 7
The late Derrick Thomas of the Kansas City Chiefs holds the single game NFL record for sacks with 7 against the Seattle Seahawks in 1990.
"Mean" Joe Greene holds the record for most sacks in a month for the Pittsburgh Steelers.
the green bay packers hold it at 16 in a game
packers
7 sacks by Derrick Thomas played on Kansas Cheifs
Derrick Thomas with 7
The late Derrick Thomas of the Kansas City Chiefs holds the single game NFL record for sacks with 7 against the Seattle Seahawks in 1990.
"Mean" Joe Greene holds the record for most sacks in a month for the Pittsburgh Steelers.
osi unenora 6 SACKS AGAINST EAGLES IN 2007.
the green bay packers hold it at 16 in a game
Kamerion Wimbley holds the record for the most sacks in one game by a Raider in one game of football. The game was played on November 10, 2011 against the San Diego Chargers. He had 4 sacks that game.
probably auburn vs alabama 2005 auburn had 11 sacks in that game war eagle.
Willie McGinest holds the record for most sacks in a playoff game, with 4 1/2. He accomplished this on January 7, 2006 versus the Jacksonville Jaguars.
The 1984 Chicago Bears who had 72 sacks.
Bruce smith