Lou Gehrig holds the record for most grand slams in a career at 23, but Alex Rodriguez has a reasonable chance of breaking that. Check the link below for a list of every MLB player who has hit at least two grand slams in a career. This includes Tony Cloninger, a pitcher who hit two grand slams in one game -- and hit only nine other home runs in his entire career.
New York Yankees hit 3 Grand Slam in 1 game
The 1996 Detroit Tigers gave up 14 Grand Slams for the Major League record. The NL record is 12 by the team formerly known as the Montreal Expos in 2000.chris dixonsilverdale, WA
In MLB, the career record for grand slams hit by a pitcher is 2 and has been done by 6 pitchers: Dizzy Trout, Camilo Pascual, Bob Gibson, Tony Cloninger, Rick Wise, and Denny Neagle. Cloninger hit both of his grand slams in the same game.
Through the 2013 season, there were 6452 grand slams hit in baseball history. The most grand slams in a season happened in the year 2000 when 176 grand slams were hit.
Lou Gehrig, with 23 Grand Slams
Roger Federer: 16 grand slams
Lou Gehrig with 23 grand slams
Roger Federer with 15 Grand Slams
The doubles pair who have won the most Grand Slams is Bob Bryan and Mike Bryan. Todd Woodbridge and Mike Woodforde have also won a large number of Grand Slams.
Pete Sampras and Roger Federer both have 14 grand slams each.
As of 04AUG09, Albert Pujols has 11 career grand slams. That is the most by any St. Louis Cardinal in history. So far, he has 5 grand slams in the 2009 season.