How many 500-yard passing games have there been in the NFL?

Answer 1

As of October 30, 2016, 18 NFL quarterbacks have had 500-plus passing yards in one game. Ben Roethlisberger of the Pittsburgh Steelers and Drew Brees of the New Orleans Saints each accomplished the feat twice:
1) 554 - Norm Van Brocklin of the Los Angeles Rams against the New York Yanks on September 28, 1951. The Rams won 54-14.
2) 527 - Warren Moon of the Houston Oilers against the Kansas City Chiefs on December 16, 1990. The Oilers won 27-10.
2) 527 - Matt Shaub of the Houston Texans against the Jacksonville Jaguars on November 18, 2012. The Texans won 43-37 in overtime.
4) 522 - Boomer Esiason of the Arizona Cardinals against the Washington Redskins on November 10, 1996. The Cardinals won 37-34.
4) 522 - Ben Roethlisberger of the Pittsburgh Steelers against the Indianapolis Colts on October 26, 2014. The Steelers won 51-34.
6) 521 - Dan Marino of the Miami Dolphins against the New York Jets on October 23, 1988. The Dolphins lost 44-30.
7) 520 - Matthew Stafford of the Detroit Lions against the Green Bay Packers on January 1, 2012. The Lions lost 45-41.
8) 517 - Tom Brady of the New England Patriots against the Miami Dolphins. The Patriots won 38-24.
9) 513 - Derek Carr of the Oakland Raiders against the Tampa Bay Buccaneers on October 30, 2016. The Raiders won in overtime 30-24. 9) 513 - Phil Simms of the New York Giants against the Cincinnati Bengals on October 13, 1985. The Giants lost 35-30.

11) 510 - Drew Brees of the New Orleans Saints against the Cincinnati Bengals on November 19, 2006. The Saints lost 31-16.
11) 510 - Eli Manning of the New York Giants against the Tampa Bay Buccaneers on September 16, 2012. The Giants won 41-34.
13) 509 - Vince Ferragamo of the Los Angeles Rams against the Chicago Bears on December 26, 1982. The Rams lost 34-26.
14) 506 -- Tony Romo of the Dallas Cowboys against the Denver Broncos on October 6, 2013. The Cowboys lost 51-48.
15) 505 - Drew Brees of the New Orleans Saints against the New York Giants on November 1, 2015. The Saints won 52-49.
15) 505 - Y.A. Tittle of the New York Giants against the Washington Redskins on October 28, 1962. The Giants won 49-34.
17) 504 - Elvis Grbac of the Kansas City Chiefs against the Oakland Raiders on November 5, 2000. The Chiefs lost 49-31.
18) 503 -- Matt Ryan of the Atlanta Falcons against the Carolina Panthers on October 2, 2016. The Falcons won 48-33.
18) 503 -- Philip Rivers of the San Diego Chargers against the Green Bay Packers on October 18, 2015. The Packer won 27-20.
18) 503 - Ben Roethlisberger of the Pittsburgh Steelers against the Green Bay Packers on December 20, 2009. The Steelers won 37-36.

Answer 2

Through the 2011 season, there have been twelve 500 yard passing games in the NFL.

1. Norm Van Brocklin (9/28/51) - 554 yards
2. Y.A. Tittle (10/28/62) - 505 yards
3. Vince Ferragamo (12/26/82) - 509 yards
4. Phil Simms (10/13/85) - 513 yards
5. Dan Marino (10/23/88) - 521 yards
6. Warren Moon (12/16/90) - 527 yards
7. Boomer Esiason (11/10/96) - 522 yards
8. Elvis Grbac (11/5/00) - 504 yards
9. Drew Brees (11/19/06) - 510 yards
10. Ben Roethlisberger (12/20/09) - 503 yards
11. Tom Brady (9/12/11) - 517 yards
12. Matthew Stafford (01/01/12) - 520 yards

Answer 3

Norm Van Brocklin got 554 passing yards playing for the LA Rams against the NY Yanks in 1951

Answer 4

Four. Dan Marino, John Elway, Brett Favre and Peyton Manning.