Rogers Hornsby is the most common answer to that question. Rogers hit .358 (second highest career average), with a career OPS over a thousand. He is often considered the greatest right handed hitter in Baseball history.
bobby doer
The Yankee's second baseman is Robinson Cano.
Joe Castle
Robbie Alomar (probably the best second baseman ever)
Ronnie Billiard was the Cardinals second baseman in 2006. In 2005 Mark Grudzielanek was the Cardinals second baseman. The Cardinals current second baseman is Mark Ellis.
Jackie Hayes - second baseman - was born in 1906.
Jackie Hayes - second baseman - died in 1983.
He is definately the most decorated, and one of the best. It is up for debate whether he is the best ever at 3rd base.
Al Martin - second baseman - was born in 1847-09.
second baseman
In 2009, Robinson Cano was the starting second baseman for the Yankees.
Dave Howard - second baseman - died on 1956-01-26.