The Detroit Lions, with 109 losses since 2000.
New Enland Patriots.
All MLB teams playing in 2012 have lost 100+ games in a season at least once except for the Angels who entered MLB in 1961. Their most losses in a season is 95 in 1968 and 1980. The Dodgers have not lost 100+ games in a season since 1908 when they played in Brooklyn and were known as the Superbas. The Cardinals have not lost 100+ games in a season since 1908. The Yankees have not lost 100+ games in a season since 1912 when they were known as the Highlanders. The Giants have lost 100 games in a season once, that being in 1985.
Now in 2012, The Colombus Blue Jackets has lost most of their games.
the state that's gained the most in population since 2000 the state that's gained the most in population since 2000
The New York Yankees have lost 88 World Series games. Of course, they have been in 39 World Series so it would only make sense that they have lost the most games. They have also won the most World Series games with 130.