Brett Favre holds the record with 464 touchdown passes.
Andre Woodson, a quarterback from Kentucky holds the record for most touchdown passes in a season with 40 in 2007
Tom Brady set the record for most TD passes with 50 in an NFL season on December 29, 2007. Peyton Manning previously held the record for most touchdown passes in a season with 49 in 2004. Brett Favre holds the career NFL record with 508 touchdown passes.
Brett Favre currently holds this record having thrown 442 touchdown passes in his career.
The record for most touchdown passes in a single Super Bowl belongs to Steve Young with 6. Joe Montana is second, with 5. Joe Montana holds the record for most career touchdown passes in a Super Bowl with 11.
Brett Favre holds the record for most career touchdown passes with 508. He officially filed his retirement papers with the NFL on January 17, 2011.As of January 03, 2010, Brett Favre has thrown 497 career touchdown passes. He threw for 33 touchdowns in 2009 with only 7 interceptions.He threw for an avg of 7.9 yards per pass, the most in his career. His QB rating of 107.2 was the highest in his career.-------------As of September 30, 2007, Brett Favre has the most NFL touchdown passes with a total of 421.Brett Favre with 508 touchdown passes
Tom Brady if your talking about touchdown passes.