In 2006, the third seeded (in the Minneapolis bracket) University of Florida gators defeated the #2 seeded UCLA (in the Oakland bracket) in the national championship. Neither team was a number one seeed
Michigan was a #3 seed when they won the NCAA Men's Basketball Tournament in 1989.
16 seed, beat duke last year
Villanova
Kentucky
Kansas was the #6 seed in the Midwest bracket in 1988.
No, Kentucky did not play in the NCAA tournament last year. They played in the NIT.
#1 seeded Kansas defeated Kentucky in the second round of the 2007 NCAA Tournament, by a score of 88-76.
16 seeded Harvard defeated 1 seed Stanford in the 1998 women's NCAA tournament. That is the only victory by a 16 seed in either the men's or women's tournament.
The higher seed is considered the home team
The Sixth-seeded North Carolina State Wolfpack defeated the one-seed Houston Cougars in the 1983 NCAA Championship on a last second tip-in by Lorenzo Charles. This is considered one of the biggest upsets in NCAA Tournament history.
St. John's last appearance in the NCAA Men's Basketball Tournament was in 2002.
duke