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The first regular season game the Patriots played was September 9, 1960 and they lost to the Denver Broncos 13-10.

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17y ago

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More answers

They lost to the Broncos 24-30 in overtime.

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9y ago
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24-21, PATRIOTS WIN!

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16y ago
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38-20 Patriots.

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12y ago
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20-17 Patriots over Rams.

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14y ago
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Q: What was the score of the first super bowl that the patriots have won?
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