The largest margin of victory was 30 pts in a champtionship game. Not sure about just tournament games.
30 points. the 1990 ncaa championship. UNLV beat Duke
UNC in 2009 with a 20.2 average margin of victory
UCLA has the record for winning by 49 points
In 1963, Loyola set the NCAA tournament record for largest margin of victory (69 points) with a 111-42 victory over Tennessee Tech in the first round.
The largest margin of victory in the men's final was in 1990 when UNLV beat Duke by 30, 103-73.
UNLV Running Rebels
I'm pretty sure UNLV beat Duke by 30pts in the 1990 title game
The Georgia Tech Yellow Jackets once won a game 222-0 and the game was even called in the third quarter...!
U Conn 105; Idaho 37 - 68 points - 3/23/2013
The 1990 champion was the UNLV runnin' rebels over Duke by a score of 103-73 which is also the largest margin of victory ever.
117 for a D-I team, Long Island University over Medgar Evers 123 overall, Lincoln (PA) over Ohio State-Marion