In Division 1-A, that was when Michigan State, losing 38-3 to Northwestern in the 3rd quarter, scored 38 unanswered points to win 41-38 on October 21, 2006.
The Kansas Jayhawks beat MU by 10 tds in 1998.
University of Michigan (in Ann Arbor)
the biggest blowout in ncaa basketball in 2011 was 107 to 56
biggest college football fan base list
University of Notre Dame
The largest shutout in NCAA football history was a 2008 game between USC and Washington. The USC Trojans beat Washington State 69-0.
Northern Iowa's victory over Kansas