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The most is four home runs in a single game. The following players have accomplished it:

Lou Gehrig, New York, 06/03/1932

Pat Seerey, Chicago, 07/18/1948

Rocky Colavito, Cleveland, 06/10/1959

Mike Cameron, Seattle, 05/02/2002

Carlos Delgado, Toronto, 09/25/2003

Bobby Lowe, Boston, 05/30/1894

Ed Delahanty, Philadelphia, 07/13/1896

Chuck Klein, Philadelphia, 07/10/1936

Gil Hodgers, Brooklyn, 08/31/1950

Joe Adcock, Milwaukee, 07/31/1954

Willie Mays, San Francisco, 04/30/1961

Mike Schmidt, Philadelphia, 04/17/1976

Bob Horner, Atlanta, 07/06/1986

Mark Whiten, St. Louis, 09/07/1993

Shawn Green, Los Angeles, 05/23/2002

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15y ago
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11y ago

Sixteen players have hit four home runs in a game. The last player to do it was Josh Hamilton of the Texas Rangers in MaY 2012.

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13y ago

Stan Musial of the St. Louis Cardinals and Nate Colbert of the San Diego Padres each hit five home runs in one double header.

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14y ago

Frank Robinson and Ken Griffey Jr. has the record for most home runs hit on opening day with 8.

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16y ago

62 Home runs were hit on July 2, 2002.

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Q: What is the record for number of home runs in a single MLB game?
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