On November 4, 2007, rookie running back Adrian Peterson of the Minnesota Vikings rushed 30 times for 296 yards and three touchdowns against the San Diego Chargers in Minneapolis. The effort broke the NFL single-game rushing record of 295, set by Baltimore Ravens running back Jamal Lewis in 2003.
As of the 2008 season, that is Adrian Peterson of the Vikings who rushed for 296 yards in a game against the Chargers in 2007.
Minnesota Viking Adrian Peterson, 296 yards, November 4, 2007 vs. San Diego Chargers. He was a rookie at the time.
6 by Ernie Nevers of the Chicago Cardinals in a game against the Chicago Bears in 1929.
Adrian Peterson in 2007, he rushed for 296 yards vs the San Diego Chargers defense.
Timmy Smith of the Washington Redskins rushed for 204 yards in Super Bowl XXII when the 'Skins beat the Denver Broncos 42-10.
That number is 305.
John Riggins
Most rushing yards, game: 314, Eddie George(November 11, 1995 vs. Illinois)
Marcus depree
Ted Gin Jr. had the most he returned to kick returns back for over 200 yards.
Drew Bledsoe has the most negative rushing yards in NFL history.
jamal Lewis had 295 yards 4 the Baltimore ravens
Most rushing yards, game: 314, Eddie George(November 11, 1995 vs. Illinois)
O.J. Simpson with 2003 rushing yards for the 1973 Buffalo Bills.
Cory dillon
chris Johnson
All-time rushing yards (16,726; now surpassed), Most 100-yard rushing games (77), and Most yards gained rushing in a game (275; now surpassed).
Adrian Peterson - 296 Rushing yards on November 4th 2007 against the San Diego Chargers
Drew Bledsoe has the most negative rushing yards in NFL history.
Marcus depree
From most news Willie Parker of the Pittsburgh Steelers.
Drew Bledsoe has the most negative rushing yards in NFL history.
Rashard Mendenhall had the most rushing yards with 63 yards in Super Bowl XLV.
Ted Gin Jr. had the most he returned to kick returns back for over 200 yards.