Wilt Chamberlain scored 100 points in a single game.
The most runs scored by the Padres in a single game was 20 against the Expos in May, 2001 and against the Marlins in July, 1996. http://sandiego.padres.mlb.com/sd/history/single_game_records.jsp
The hockey team which has scored the most goals in a single game is the Montreal Canadians. They scored sixteen goals against the Quebec Bulldogs in 1920.
Wilt Chamberlain scored 100 points in a single NBA game and the second most in the NBA was scored by Kobe Bryant as he scored 81 in a single game.
The most runs scored in a single game by a single player since 1950 was 7 done by Boston's Spike Owen in 1986.
The Detroit Pistons scored the most points in a great game at the Denver Nuggets.