The lowest seeded team to make it all the way to the Final Four in the NCAA basketball tournament was an 11 seed and it happened four times:11 seeded LSU in 198611 seeded George Mason in 200611 seeded VCU in 201111 seeded Wichita State in 2013
8th, the lowest seed to win it all
Villanova (#8) in 1985
8 seeded Vilanova in 1985
8 Villanova over Georgetown
George Mason was the 11th seed in 2006 and made it all the way to the Final Four. I don't know if that's the lowest seeded team to make it to the Elite Eight or Final Four though.http://a.espncdn.com/ncaatourney/brackets/2006Bracket.pdf
Since the NCAA implemented the 64 seed tournament format in 1985, the lowest seed to make it to the NCAA championship game was #8 seeded Villanova in 1985.
16 seed, beat duke last year
Michigan was a #3 seed when they won the NCAA Men's Basketball Tournament in 1989.
Villanova
Since the seeding system was introduced in 1979, the lowest seed to win the NCAA men's basketball tournament was 8th-seeded Villanova in 1985.
Kansas was the #6 seed in the Midwest bracket in 1988.