4-3 in favor of Michigan State.
As of the start of the 2007 season, according to College Football Data Warehouse, Michigan State's all time record was 596-412-44.
Michigan 64-49 vs Ohio state
Michigan leads 67-29-5, at least in football.
According to College Football Data Warehouse, Florida State and Michigan State have met twice (in 1987 and 1988) and Florida State won both games.
Michigan leads the series with a 48-12-1 record.
Michigan is the all-time winningest team in college football, their overall record is 884-308-36. Alternatively Michigan State (which is traditionally a Big Ten bottom dweller) has an overall record of 627-426-44.So, in short, Michigan has 257 more wins than Michigan State.And in the famous rivalry, Michigan has beaten State twice as many times.
Iowa leads the series 21-18 with 2 ties
Michigan leads 2-3-1
The last time Michigan State beat Ohio State was in 1999 in East Lansing, Michigan.